I'm a big fan of ClearType. Don't know exactly what wizardry Microsoft is trying to pull off, or if they deserve a patent, but I do know that if you're running XP, ClearType is hot.
With Windows XP, ClearType delivers improved font display quality over traditional forms of font smoothing or anti-aliasing. ClearType improves readability on color LCD displays with a digital interface, such as those in laptops and high-quality flat panel displays. Readability on CRT screens can also be somewhat improved.
[ ClearType Step 1: Turn on Windows XP ClearType ]
Somewhat my butt. ClearType has improved my web browsing experience on every computer I use: LCD, CRT, or otherwise.
If you don't like the invasive web-based tuning tool, Microsoft has created a PowerToy as well.
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Disclaimer The opinions expressed herein are my own personal opinions.